Review




Structured Review

Santa Cruz Biotechnology rig1
A Baseline expression of LMP1, <t>RIG1,</t> EGR1, and PD-L1 in ENKTL cell lines. B Effect of EGR1 knockdown on LMP1 and PD-L1 expression. C Flow cytometric analysis of surface PD-L1 expression following EGR1 knockdown. D EGR1 overexpression-driven enhancement of LMP1 and PD-L1 in SNK6 Cells.
Rig1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 95/100, based on 123 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rig1/RIG-I+Antibody/pmc12166057-120-0-8
Average 95 stars, based on 123 article reviews
rig1 - by Bioz Stars, 2026-10
95/100 stars

Images

1) Product Images from "Early growth response 1 as a key regulator of PD-L1 expression and immune evasion in extranodal NK/T-cell lymphoma"

Article Title: Early growth response 1 as a key regulator of PD-L1 expression and immune evasion in extranodal NK/T-cell lymphoma

Journal: Blood Cancer Journal

doi: 10.1038/s41408-025-01313-w

A Baseline expression of LMP1, RIG1, EGR1, and PD-L1 in ENKTL cell lines. B Effect of EGR1 knockdown on LMP1 and PD-L1 expression. C Flow cytometric analysis of surface PD-L1 expression following EGR1 knockdown. D EGR1 overexpression-driven enhancement of LMP1 and PD-L1 in SNK6 Cells.
Figure Legend Snippet: A Baseline expression of LMP1, RIG1, EGR1, and PD-L1 in ENKTL cell lines. B Effect of EGR1 knockdown on LMP1 and PD-L1 expression. C Flow cytometric analysis of surface PD-L1 expression following EGR1 knockdown. D EGR1 overexpression-driven enhancement of LMP1 and PD-L1 in SNK6 Cells.

Techniques Used: Expressing, Knockdown, Over Expression

Related Articles

Expressing:

Article Title: Early growth response 1 as a key regulator of PD-L1 expression and immune evasion in extranodal NK/T-cell lymphoma
Article Snippet: PTEN (cs#9188), p-AKT S473 (cs#4058), AKT (cs#9272), p-STAT3 T705 (cs#9145), β-actin (cs#4970), and vinculin (cs#9145) were purchased from Cell Signaling Technology (Beverly, MA, USA).PTEN (cs#9188), p-AKT S473 (cs#4058), AKT (cs#9272), p-STAT3 T705 (cs#9145), β-actin (cs#4970), and vinculin (cs#9145) were purchased from Cell Signaling Technology (Beverly, MA, USA).. RIG1 (sc-376845) and GAPDH (sc25778) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA).. The BCA protein assay kit (BCA0500) and enhanced chemiluminescence (ECL, BWF0100) were purchased from BIOMAX (Guri, Republic of Korea).The BCA protein assay kit (BCA0500) and enhanced chemiluminescence (ECL, BWF0100) were purchased from BIOMAX (Guri, Republic of Korea).

Article Title: Early growth response 1 as a key regulator of PD-L1 expression and immune evasion in extranodal NK/T-cell lymphoma.
Article Snippet: PTEN (cs#9188), p-AKT S473 (cs#4058), AKT (cs#9272), p-STAT3 T705 (cs#9145), β-actin (cs#4970), and vinculin (cs#9145) were purchased from Cell Signaling Technology (Beverly, MA, USA).PTEN (cs#9188), p-AKT S473 (cs#4058), AKT (cs#9272), p-STAT3 T705 (cs#9145), β-actin (cs#4970), and vinculin (cs#9145) were purchased from Cell Signaling Technology (Beverly, MA, USA).. RIG1 (sc-376845) and GAPDH (sc25778) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA).. The BCA protein assay kit (BCA0500) and enhanced chemiluminescence (ECL, BWF0100) were purchased from BIOMAX (Guri, Republic of Korea).The BCA protein assay kit (BCA0500) and enhanced chemiluminescence (ECL, BWF0100) were purchased from BIOMAX (Guri, Republic of Korea).

Article Title: ADARp150 counteracts whole genome duplication
Article Snippet: Primary antibodies used: ADAR1 (Santa Cruz Biotechnology Cat# sc-73408, RRID: AB_2222767), RB1 (Santa Cruz Biotechnology Cat# sc-50-G, RRID:AB_632340 ), RBL1 (Santa Cruz Biotechnology Cat# sc-318, RRID: AB_2175428), RBL2 (D09855-2 Oncogene), BCL2 (Santa Cruz Biotechnology Cat# sc-509, RRID: AB_626733), p53 (BD Biosciences Cat# 554293, RRID: AB_395348), IFNAR1 (Thermo Fisher Scientific Cat# PA5-79441, RRID: AB_2746557), MDA5 (Cell Signaling Technology Cat# 5321 (also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell Signaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB_2798941 ), ZBP1 (Novus Cat# NBP1-76854, RRID: AB_11018813).Signaling Technology Cat# 5321 (also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell Signaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB_2798941 ), ZBP1 (Novus Cat# NBP1-76854, RRID: AB_11018813). ... Primary antibodies that, in our study, did not detect the antibody of interest: ADAR1 (Santa Cruz Biotechnology Cat# sc-271854, RRID: AB_10708553), IFNAR1 (Santa Cruz Biotechnology Cat# sc-7391, RRID: AB_2122749, Thermo Fisher Scientific Cat# MA5-43696, RRID: AB_2912628), RIG1 (Santa Cruz Biotechnology Cat# sc-376845, RRID: AB_2732794), ZBP1 (Cell Signaling Technology Cat# 60968, RRID: AB_2799599, AdipoGen Cat# AG-20B-0010 (also AG-20B-0010-C100), RRID: AB_2490191).. IR Dye 800CW secondary igG antibodies (LI-COR) were used.IR Dye 800CW secondary igG antibodies (LI-COR) were used.

Article Title: ADARp150 counteracts whole genome duplication.
Article Snippet: Primary antibodies used: ADAR1 (Santa Cruz iotechnology Cat# sc-73408, RRID: AB_2222767), RB1 Santa Cruz Biotechnology Cat# sc-50-G, RRID:AB _ 632340 ), BL1 (Santa Cruz Biotechnology Cat# sc-318, RRID: B_2175428), RBL2 (D09855-2 Oncogene), BCL2 (Santa ruz Biotechnology Cat# sc-509, RRID: AB_626733), p53 BD Biosciences Cat# 554293, RRID: AB_395348), IFAR1 (Thermo Fisher Scientific Cat# PA5-79441, RRID: B_2746557), MDA5 (Cell Signaling Technology Cat# 5321 also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell ignaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB _ 2798941 ), ZBP1 (Novus Cat# NBP176854, RRID: AB_11018813).Cat# 5321 also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell ignaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB _ 2798941 ), ZBP1 (Novus Cat# NBP176854, RRID: AB_11018813). ... Primary antibodies that, in our study, did not detect the antibody of interest: ADAR1 (Santa Cruz Biotechnology Cat# sc-271854, RRID: AB_10708553), IFNAR1 (Santa Cruz Biotechnology Cat# sc-7391, RRID: AB_2122749, Thermo Fisher Scientific Cat# MA5-43696, RRID: AB_2912628), RIG1 (Santa Cruz Biotechnology Cat# sc-376845, RRID: AB_2732794), ZBP1 (Cell Signaling Technology Cat# 60968, RRID: AB_2799599, AdipoGen Cat# AG-20B-0010 (also AG-20B-0010-C100), RRID: AB_2490191).. IR Dye 800CW secondary igG antibodies (LI-COR) were used.IR Dye 800CW secondary igG antibodies (LI-COR) were used.

Article Title: ADARp150 counteracts whole genome duplication.
Article Snippet: 20 μg proein was loaded onto 4–12% NuPAGE Bis–Tris gels (Life echnologies).20 μg proein was loaded onto 4–12% NuPAGE Bis–Tris gels (Life echnologies).. Primary antibodies used: ADAR1 (Santa Cruz iotechnology Cat# sc-73408, RRID: AB_2222767), RB1 Santa Cruz Biotechnology Cat# sc-50-G, RRID:AB _ 632340 ), BL1 (Santa Cruz Biotechnology Cat# sc-318, RRID: B_2175428), RBL2 (D09855-2 Oncogene), BCL2 (Santa ruz Biotechnology Cat# sc-509, RRID: AB_626733), p53 BD Biosciences Cat# 554293, RRID: AB_395348), IFAR1 (Thermo Fisher Scientific Cat# PA5-79441, RRID: B_2746557), MDA5 (Cell Signaling Technology Cat# 5321 also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell ignaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB _ 2798941 ), ZBP1 (Novus Cat# NBP176854, RRID: AB_11018813).. Primary antibodies that, in our study, did not detect the antibody of interest: ADAR1 (Santa Cruz Biotechnology Cat# sc-271854, RRID: AB_10708553), IFNAR1 (Santa Cruz Biotechnology Cat# sc-7391, RRID: AB_2122749, Thermo Fisher Scientific Cat# MA5-43696, RRID: AB_2912628), RIG1 (Santa Cruz Biotechnology Cat# sc-376845, RRID: AB_2732794), ZBP1 (Cell Signaling Technology Cat# 60968, RRID: AB_2799599, AdipoGen Cat# AG-20B-0010 (also AG-20B-0010-C100), RRID: AB_2490191).Primary antibodies that, in our study, did not detect the antibody of interest: ADAR1 (Santa Cruz Biotechnology..

Article Title: The DNA repair enzyme, aprataxin, plays a role in innate immune signaling
Article Snippet: Primary antibodies used were STING (13647S), phospho-STING (Ser366, 19781S), TBK1 (3504S), phospho-TBK1 (Ser172, 5483S), and phospho-IRF-3 (Ser386, 37829S) all from Cell Signaling.Primary antibodies used were STING (13647S), phospho-STING (Ser366, 19781S), TBK1 (3504S), phospho-TBK1 (Ser172, 5483S), and phospho-IRF-3 (Ser386, 37829S) all from Cell Signaling.. APTX (sc-374108), IRF3 (SL-12, sc-33641) and Rig1 (D12, sc-376845) antibodies were from Santa Cruz and Actin (A5441) was from Merck.. GraphPad Prism V9.2 was used for plotting and performing two-way ANOVA analysis.GraphPad Prism V9.2 was used for plotting and performing two-way ANOVA analysis.

Knockdown:

Article Title: Early growth response 1 as a key regulator of PD-L1 expression and immune evasion in extranodal NK/T-cell lymphoma
Article Snippet: PTEN (cs#9188), p-AKT S473 (cs#4058), AKT (cs#9272), p-STAT3 T705 (cs#9145), β-actin (cs#4970), and vinculin (cs#9145) were purchased from Cell Signaling Technology (Beverly, MA, USA).PTEN (cs#9188), p-AKT S473 (cs#4058), AKT (cs#9272), p-STAT3 T705 (cs#9145), β-actin (cs#4970), and vinculin (cs#9145) were purchased from Cell Signaling Technology (Beverly, MA, USA).. RIG1 (sc-376845) and GAPDH (sc25778) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA).. The BCA protein assay kit (BCA0500) and enhanced chemiluminescence (ECL, BWF0100) were purchased from BIOMAX (Guri, Republic of Korea).The BCA protein assay kit (BCA0500) and enhanced chemiluminescence (ECL, BWF0100) were purchased from BIOMAX (Guri, Republic of Korea).

Article Title: Early growth response 1 as a key regulator of PD-L1 expression and immune evasion in extranodal NK/T-cell lymphoma.
Article Snippet: PTEN (cs#9188), p-AKT S473 (cs#4058), AKT (cs#9272), p-STAT3 T705 (cs#9145), β-actin (cs#4970), and vinculin (cs#9145) were purchased from Cell Signaling Technology (Beverly, MA, USA).PTEN (cs#9188), p-AKT S473 (cs#4058), AKT (cs#9272), p-STAT3 T705 (cs#9145), β-actin (cs#4970), and vinculin (cs#9145) were purchased from Cell Signaling Technology (Beverly, MA, USA).. RIG1 (sc-376845) and GAPDH (sc25778) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA).. The BCA protein assay kit (BCA0500) and enhanced chemiluminescence (ECL, BWF0100) were purchased from BIOMAX (Guri, Republic of Korea).The BCA protein assay kit (BCA0500) and enhanced chemiluminescence (ECL, BWF0100) were purchased from BIOMAX (Guri, Republic of Korea).

Article Title: ADARp150 counteracts whole genome duplication
Article Snippet: Primary antibodies used: ADAR1 (Santa Cruz Biotechnology Cat# sc-73408, RRID: AB_2222767), RB1 (Santa Cruz Biotechnology Cat# sc-50-G, RRID:AB_632340 ), RBL1 (Santa Cruz Biotechnology Cat# sc-318, RRID: AB_2175428), RBL2 (D09855-2 Oncogene), BCL2 (Santa Cruz Biotechnology Cat# sc-509, RRID: AB_626733), p53 (BD Biosciences Cat# 554293, RRID: AB_395348), IFNAR1 (Thermo Fisher Scientific Cat# PA5-79441, RRID: AB_2746557), MDA5 (Cell Signaling Technology Cat# 5321 (also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell Signaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB_2798941 ), ZBP1 (Novus Cat# NBP1-76854, RRID: AB_11018813).Signaling Technology Cat# 5321 (also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell Signaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB_2798941 ), ZBP1 (Novus Cat# NBP1-76854, RRID: AB_11018813). ... Primary antibodies that, in our study, did not detect the antibody of interest: ADAR1 (Santa Cruz Biotechnology Cat# sc-271854, RRID: AB_10708553), IFNAR1 (Santa Cruz Biotechnology Cat# sc-7391, RRID: AB_2122749, Thermo Fisher Scientific Cat# MA5-43696, RRID: AB_2912628), RIG1 (Santa Cruz Biotechnology Cat# sc-376845, RRID: AB_2732794), ZBP1 (Cell Signaling Technology Cat# 60968, RRID: AB_2799599, AdipoGen Cat# AG-20B-0010 (also AG-20B-0010-C100), RRID: AB_2490191).. IR Dye 800CW secondary igG antibodies (LI-COR) were used.IR Dye 800CW secondary igG antibodies (LI-COR) were used.

Article Title: ADARp150 counteracts whole genome duplication.
Article Snippet: Primary antibodies used: ADAR1 (Santa Cruz iotechnology Cat# sc-73408, RRID: AB_2222767), RB1 Santa Cruz Biotechnology Cat# sc-50-G, RRID:AB _ 632340 ), BL1 (Santa Cruz Biotechnology Cat# sc-318, RRID: B_2175428), RBL2 (D09855-2 Oncogene), BCL2 (Santa ruz Biotechnology Cat# sc-509, RRID: AB_626733), p53 BD Biosciences Cat# 554293, RRID: AB_395348), IFAR1 (Thermo Fisher Scientific Cat# PA5-79441, RRID: B_2746557), MDA5 (Cell Signaling Technology Cat# 5321 also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell ignaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB _ 2798941 ), ZBP1 (Novus Cat# NBP176854, RRID: AB_11018813).Cat# 5321 also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell ignaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB _ 2798941 ), ZBP1 (Novus Cat# NBP176854, RRID: AB_11018813). ... Primary antibodies that, in our study, did not detect the antibody of interest: ADAR1 (Santa Cruz Biotechnology Cat# sc-271854, RRID: AB_10708553), IFNAR1 (Santa Cruz Biotechnology Cat# sc-7391, RRID: AB_2122749, Thermo Fisher Scientific Cat# MA5-43696, RRID: AB_2912628), RIG1 (Santa Cruz Biotechnology Cat# sc-376845, RRID: AB_2732794), ZBP1 (Cell Signaling Technology Cat# 60968, RRID: AB_2799599, AdipoGen Cat# AG-20B-0010 (also AG-20B-0010-C100), RRID: AB_2490191).. IR Dye 800CW secondary igG antibodies (LI-COR) were used.IR Dye 800CW secondary igG antibodies (LI-COR) were used.

Article Title: ADARp150 counteracts whole genome duplication.
Article Snippet: 20 μg proein was loaded onto 4–12% NuPAGE Bis–Tris gels (Life echnologies).20 μg proein was loaded onto 4–12% NuPAGE Bis–Tris gels (Life echnologies).. Primary antibodies used: ADAR1 (Santa Cruz iotechnology Cat# sc-73408, RRID: AB_2222767), RB1 Santa Cruz Biotechnology Cat# sc-50-G, RRID:AB _ 632340 ), BL1 (Santa Cruz Biotechnology Cat# sc-318, RRID: B_2175428), RBL2 (D09855-2 Oncogene), BCL2 (Santa ruz Biotechnology Cat# sc-509, RRID: AB_626733), p53 BD Biosciences Cat# 554293, RRID: AB_395348), IFAR1 (Thermo Fisher Scientific Cat# PA5-79441, RRID: B_2746557), MDA5 (Cell Signaling Technology Cat# 5321 also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell ignaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB _ 2798941 ), ZBP1 (Novus Cat# NBP176854, RRID: AB_11018813).. Primary antibodies that, in our study, did not detect the antibody of interest: ADAR1 (Santa Cruz Biotechnology Cat# sc-271854, RRID: AB_10708553), IFNAR1 (Santa Cruz Biotechnology Cat# sc-7391, RRID: AB_2122749, Thermo Fisher Scientific Cat# MA5-43696, RRID: AB_2912628), RIG1 (Santa Cruz Biotechnology Cat# sc-376845, RRID: AB_2732794), ZBP1 (Cell Signaling Technology Cat# 60968, RRID: AB_2799599, AdipoGen Cat# AG-20B-0010 (also AG-20B-0010-C100), RRID: AB_2490191).Primary antibodies that, in our study, did not detect the antibody of interest: ADAR1 (Santa Cruz Biotechnology..

Article Title: The DNA repair enzyme, aprataxin, plays a role in innate immune signaling
Article Snippet: Primary antibodies used were STING (13647S), phospho-STING (Ser366, 19781S), TBK1 (3504S), phospho-TBK1 (Ser172, 5483S), and phospho-IRF-3 (Ser386, 37829S) all from Cell Signaling.Primary antibodies used were STING (13647S), phospho-STING (Ser366, 19781S), TBK1 (3504S), phospho-TBK1 (Ser172, 5483S), and phospho-IRF-3 (Ser386, 37829S) all from Cell Signaling.. APTX (sc-374108), IRF3 (SL-12, sc-33641) and Rig1 (D12, sc-376845) antibodies were from Santa Cruz and Actin (A5441) was from Merck.. GraphPad Prism V9.2 was used for plotting and performing two-way ANOVA analysis.GraphPad Prism V9.2 was used for plotting and performing two-way ANOVA analysis.

Over Expression:

Article Title: Early growth response 1 as a key regulator of PD-L1 expression and immune evasion in extranodal NK/T-cell lymphoma
Article Snippet: PTEN (cs#9188), p-AKT S473 (cs#4058), AKT (cs#9272), p-STAT3 T705 (cs#9145), β-actin (cs#4970), and vinculin (cs#9145) were purchased from Cell Signaling Technology (Beverly, MA, USA).PTEN (cs#9188), p-AKT S473 (cs#4058), AKT (cs#9272), p-STAT3 T705 (cs#9145), β-actin (cs#4970), and vinculin (cs#9145) were purchased from Cell Signaling Technology (Beverly, MA, USA).. RIG1 (sc-376845) and GAPDH (sc25778) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA).. The BCA protein assay kit (BCA0500) and enhanced chemiluminescence (ECL, BWF0100) were purchased from BIOMAX (Guri, Republic of Korea).The BCA protein assay kit (BCA0500) and enhanced chemiluminescence (ECL, BWF0100) were purchased from BIOMAX (Guri, Republic of Korea).

Article Title: Early growth response 1 as a key regulator of PD-L1 expression and immune evasion in extranodal NK/T-cell lymphoma.
Article Snippet: PTEN (cs#9188), p-AKT S473 (cs#4058), AKT (cs#9272), p-STAT3 T705 (cs#9145), β-actin (cs#4970), and vinculin (cs#9145) were purchased from Cell Signaling Technology (Beverly, MA, USA).PTEN (cs#9188), p-AKT S473 (cs#4058), AKT (cs#9272), p-STAT3 T705 (cs#9145), β-actin (cs#4970), and vinculin (cs#9145) were purchased from Cell Signaling Technology (Beverly, MA, USA).. RIG1 (sc-376845) and GAPDH (sc25778) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA).. The BCA protein assay kit (BCA0500) and enhanced chemiluminescence (ECL, BWF0100) were purchased from BIOMAX (Guri, Republic of Korea).The BCA protein assay kit (BCA0500) and enhanced chemiluminescence (ECL, BWF0100) were purchased from BIOMAX (Guri, Republic of Korea).

Article Title: ADARp150 counteracts whole genome duplication
Article Snippet: Primary antibodies used: ADAR1 (Santa Cruz Biotechnology Cat# sc-73408, RRID: AB_2222767), RB1 (Santa Cruz Biotechnology Cat# sc-50-G, RRID:AB_632340 ), RBL1 (Santa Cruz Biotechnology Cat# sc-318, RRID: AB_2175428), RBL2 (D09855-2 Oncogene), BCL2 (Santa Cruz Biotechnology Cat# sc-509, RRID: AB_626733), p53 (BD Biosciences Cat# 554293, RRID: AB_395348), IFNAR1 (Thermo Fisher Scientific Cat# PA5-79441, RRID: AB_2746557), MDA5 (Cell Signaling Technology Cat# 5321 (also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell Signaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB_2798941 ), ZBP1 (Novus Cat# NBP1-76854, RRID: AB_11018813).Signaling Technology Cat# 5321 (also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell Signaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB_2798941 ), ZBP1 (Novus Cat# NBP1-76854, RRID: AB_11018813). ... Primary antibodies that, in our study, did not detect the antibody of interest: ADAR1 (Santa Cruz Biotechnology Cat# sc-271854, RRID: AB_10708553), IFNAR1 (Santa Cruz Biotechnology Cat# sc-7391, RRID: AB_2122749, Thermo Fisher Scientific Cat# MA5-43696, RRID: AB_2912628), RIG1 (Santa Cruz Biotechnology Cat# sc-376845, RRID: AB_2732794), ZBP1 (Cell Signaling Technology Cat# 60968, RRID: AB_2799599, AdipoGen Cat# AG-20B-0010 (also AG-20B-0010-C100), RRID: AB_2490191).. IR Dye 800CW secondary igG antibodies (LI-COR) were used.IR Dye 800CW secondary igG antibodies (LI-COR) were used.

Article Title: ADARp150 counteracts whole genome duplication.
Article Snippet: Primary antibodies used: ADAR1 (Santa Cruz iotechnology Cat# sc-73408, RRID: AB_2222767), RB1 Santa Cruz Biotechnology Cat# sc-50-G, RRID:AB _ 632340 ), BL1 (Santa Cruz Biotechnology Cat# sc-318, RRID: B_2175428), RBL2 (D09855-2 Oncogene), BCL2 (Santa ruz Biotechnology Cat# sc-509, RRID: AB_626733), p53 BD Biosciences Cat# 554293, RRID: AB_395348), IFAR1 (Thermo Fisher Scientific Cat# PA5-79441, RRID: B_2746557), MDA5 (Cell Signaling Technology Cat# 5321 also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell ignaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB _ 2798941 ), ZBP1 (Novus Cat# NBP176854, RRID: AB_11018813).Cat# 5321 also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell ignaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB _ 2798941 ), ZBP1 (Novus Cat# NBP176854, RRID: AB_11018813). ... Primary antibodies that, in our study, did not detect the antibody of interest: ADAR1 (Santa Cruz Biotechnology Cat# sc-271854, RRID: AB_10708553), IFNAR1 (Santa Cruz Biotechnology Cat# sc-7391, RRID: AB_2122749, Thermo Fisher Scientific Cat# MA5-43696, RRID: AB_2912628), RIG1 (Santa Cruz Biotechnology Cat# sc-376845, RRID: AB_2732794), ZBP1 (Cell Signaling Technology Cat# 60968, RRID: AB_2799599, AdipoGen Cat# AG-20B-0010 (also AG-20B-0010-C100), RRID: AB_2490191).. IR Dye 800CW secondary igG antibodies (LI-COR) were used.IR Dye 800CW secondary igG antibodies (LI-COR) were used.

Article Title: ADARp150 counteracts whole genome duplication.
Article Snippet: 20 μg proein was loaded onto 4–12% NuPAGE Bis–Tris gels (Life echnologies).20 μg proein was loaded onto 4–12% NuPAGE Bis–Tris gels (Life echnologies).. Primary antibodies used: ADAR1 (Santa Cruz iotechnology Cat# sc-73408, RRID: AB_2222767), RB1 Santa Cruz Biotechnology Cat# sc-50-G, RRID:AB _ 632340 ), BL1 (Santa Cruz Biotechnology Cat# sc-318, RRID: B_2175428), RBL2 (D09855-2 Oncogene), BCL2 (Santa ruz Biotechnology Cat# sc-509, RRID: AB_626733), p53 BD Biosciences Cat# 554293, RRID: AB_395348), IFAR1 (Thermo Fisher Scientific Cat# PA5-79441, RRID: B_2746557), MDA5 (Cell Signaling Technology Cat# 5321 also 5321S), RRID: AB_10694490), RIG1 (D1466 Cell ignaling), PKR (Santa Cruz Biotechnology Cat# sc-6282, RRID: AB_628150), RNAseL (Cell Signaling Technology Cat# 27281, RRID:AB _ 2798941 ), ZBP1 (Novus Cat# NBP176854, RRID: AB_11018813).. Primary antibodies that, in our study, did not detect the antibody of interest: ADAR1 (Santa Cruz Biotechnology Cat# sc-271854, RRID: AB_10708553), IFNAR1 (Santa Cruz Biotechnology Cat# sc-7391, RRID: AB_2122749, Thermo Fisher Scientific Cat# MA5-43696, RRID: AB_2912628), RIG1 (Santa Cruz Biotechnology Cat# sc-376845, RRID: AB_2732794), ZBP1 (Cell Signaling Technology Cat# 60968, RRID: AB_2799599, AdipoGen Cat# AG-20B-0010 (also AG-20B-0010-C100), RRID: AB_2490191).Primary antibodies that, in our study, did not detect the antibody of interest: ADAR1 (Santa Cruz Biotechnology..

Article Title: The DNA repair enzyme, aprataxin, plays a role in innate immune signaling
Article Snippet: Primary antibodies used were STING (13647S), phospho-STING (Ser366, 19781S), TBK1 (3504S), phospho-TBK1 (Ser172, 5483S), and phospho-IRF-3 (Ser386, 37829S) all from Cell Signaling.Primary antibodies used were STING (13647S), phospho-STING (Ser366, 19781S), TBK1 (3504S), phospho-TBK1 (Ser172, 5483S), and phospho-IRF-3 (Ser386, 37829S) all from Cell Signaling.. APTX (sc-374108), IRF3 (SL-12, sc-33641) and Rig1 (D12, sc-376845) antibodies were from Santa Cruz and Actin (A5441) was from Merck.. GraphPad Prism V9.2 was used for plotting and performing two-way ANOVA analysis.GraphPad Prism V9.2 was used for plotting and performing two-way ANOVA analysis.



Similar Products

94
MedChemExpress rig1 inhibitor rig012
Rig1 Inhibitor Rig012, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rig1/RIG012/pm42140967-273-192-196
Average 94 stars, based on 1 article reviews
rig1 inhibitor rig012 - by Bioz Stars, 2026-10
94/100 stars
  Buy from Supplier

95
Proteintech anti rig1 antibody
Anti Rig1 Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rig1/DDX58+Antibody/10__1016_slash_j__scib__2025__09__044-104-13-16
Average 95 stars, based on 1 article reviews
anti rig1 antibody - by Bioz Stars, 2026-10
95/100 stars
  Buy from Supplier

96
Cell Signaling Technology Inc rig1 wb cell signaling technologies
Rig1 Wb Cell Signaling Technologies, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rig1/Rig-I+Rabbit+mAb/pmc12307730__41467_2025_62309_MOESM2_ESM-44-272-276
Average 96 stars, based on 1 article reviews
rig1 wb cell signaling technologies - by Bioz Stars, 2026-10
96/100 stars
  Buy from Supplier

95
Santa Cruz Biotechnology rig1
A Baseline expression of LMP1, <t>RIG1,</t> EGR1, and PD-L1 in ENKTL cell lines. B Effect of EGR1 knockdown on LMP1 and PD-L1 expression. C Flow cytometric analysis of surface PD-L1 expression following EGR1 knockdown. D EGR1 overexpression-driven enhancement of LMP1 and PD-L1 in SNK6 Cells.
Rig1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rig1/RIG-I+Antibody/pmc12166057-120-0-8
Average 95 stars, based on 1 article reviews
rig1 - by Bioz Stars, 2026-10
95/100 stars
  Buy from Supplier

94
MedChemExpress rig1 inhibitor
A Baseline expression of LMP1, <t>RIG1,</t> EGR1, and PD-L1 in ENKTL cell lines. B Effect of EGR1 knockdown on LMP1 and PD-L1 expression. C Flow cytometric analysis of surface PD-L1 expression following EGR1 knockdown. D EGR1 overexpression-driven enhancement of LMP1 and PD-L1 in SNK6 Cells.
Rig1 Inhibitor, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rig1/RIG012/pmc12159843__thnov15p6329s1-25-16-20
Average 94 stars, based on 1 article reviews
rig1 inhibitor - by Bioz Stars, 2026-10
94/100 stars
  Buy from Supplier

96
Cell Signaling Technology Inc rig1
Effect of the NLRX1 mutation on <t>MAVS/RIG1</t> and proinflammatory cytokines. Huh7-NTCP cells are transfected with WT NLRX1 or MT NLRX1 vector for 48 h. ( A ) Coimmunoprecipitation assay showing the effect of WT NLRX1 or MT NLRX1 on MAVS/RIG1 interaction. ( B ) Luciferase expression from the IFN-α, IL-6, or IFN-β promoter in Huh7-NTCP cells. All experiments were repeated three times independently. *, P < 0.05 vs. NC + HBV; **, P < 0.01 vs. NC + HBV; +, P < 0.05 vs. WT NLRX1 + HBV
Rig1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rig1/Rig-I+Rabbit+mAb/pmc11538211-55-22-23
Average 96 stars, based on 1 article reviews
rig1 - by Bioz Stars, 2026-10
96/100 stars
  Buy from Supplier

Image Search Results


A Baseline expression of LMP1, RIG1, EGR1, and PD-L1 in ENKTL cell lines. B Effect of EGR1 knockdown on LMP1 and PD-L1 expression. C Flow cytometric analysis of surface PD-L1 expression following EGR1 knockdown. D EGR1 overexpression-driven enhancement of LMP1 and PD-L1 in SNK6 Cells.

Journal: Blood Cancer Journal

Article Title: Early growth response 1 as a key regulator of PD-L1 expression and immune evasion in extranodal NK/T-cell lymphoma

doi: 10.1038/s41408-025-01313-w

Figure Lengend Snippet: A Baseline expression of LMP1, RIG1, EGR1, and PD-L1 in ENKTL cell lines. B Effect of EGR1 knockdown on LMP1 and PD-L1 expression. C Flow cytometric analysis of surface PD-L1 expression following EGR1 knockdown. D EGR1 overexpression-driven enhancement of LMP1 and PD-L1 in SNK6 Cells.

Article Snippet: RIG1 (sc-376845) and GAPDH (sc25778) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA).

Techniques: Expressing, Knockdown, Over Expression

Effect of the NLRX1 mutation on MAVS/RIG1 and proinflammatory cytokines. Huh7-NTCP cells are transfected with WT NLRX1 or MT NLRX1 vector for 48 h. ( A ) Coimmunoprecipitation assay showing the effect of WT NLRX1 or MT NLRX1 on MAVS/RIG1 interaction. ( B ) Luciferase expression from the IFN-α, IL-6, or IFN-β promoter in Huh7-NTCP cells. All experiments were repeated three times independently. *, P < 0.05 vs. NC + HBV; **, P < 0.01 vs. NC + HBV; +, P < 0.05 vs. WT NLRX1 + HBV

Journal: Archives of Virology

Article Title: An NLR family member X1 mutation ( p.Arg707Cys ) suppresses hepatitis B virus infection in hepatocytes and favors the interaction of retinoic acid-inducible gene 1 with mitochondrial antiviral signaling protein

doi: 10.1007/s00705-024-06133-0

Figure Lengend Snippet: Effect of the NLRX1 mutation on MAVS/RIG1 and proinflammatory cytokines. Huh7-NTCP cells are transfected with WT NLRX1 or MT NLRX1 vector for 48 h. ( A ) Coimmunoprecipitation assay showing the effect of WT NLRX1 or MT NLRX1 on MAVS/RIG1 interaction. ( B ) Luciferase expression from the IFN-α, IL-6, or IFN-β promoter in Huh7-NTCP cells. All experiments were repeated three times independently. *, P < 0.05 vs. NC + HBV; **, P < 0.01 vs. NC + HBV; +, P < 0.05 vs. WT NLRX1 + HBV

Article Snippet: The primary antibodies were as follows: HBcAg (Santa Cruz, #sc-23947; 1:1000); HBsAg (Santa Cruz, #sc-53299; 1:1000); NLRX1 (Proteintech, Wuhan, China, #17215-1-AP; 1:2000); RIG1 (CST, #3743T; 1:2000); MAVS (Abcam, ab31334; 1:2000); p65 (Abcam, ab7970; 1:500); p-p65 (CST, #3033S; 1:1000); IRF7 (CST, #13014; 1:1000); p-IRF7 (CST, #12390; 1:1000); IRF3 (CST, #4302; 1:1000); p-IRF3 (CST, #29047; 1:1000); and glyceraldehyde-3-phosphate dehydrogenase (GAPDH; Proteintech, 60004-1-Ig, 1:8000).

Techniques: Mutagenesis, Transfection, Plasmid Preparation, Co-Immunoprecipitation Assay, Luciferase, Expressing